SR-121463A CAS; 185913-79-

SR-121463A CAS;

价格:12000元/公斤 含量:99% 包装:25公斤

CAS;

分子式：C17H22ClNO3

分子量：323.8228

化学名称 N-tert-Butyl-4-[5'-ethoxy-4-[2-(4-morpholinyl)ethoxy]-2'-oxospiro[cyclohexane-1,3'-indolin]-

1'-ylsulfonyl]-3-methoxybenzamide fumarate

The reduction of diethyl 3-(methoxymethoxy)glutarate (I) with LiAlH4 in THF gives 3-(methoxymethoxy)pentane-

1,5-diol (II), which is treated with Ts-OH and TEA in THF to yield the disulfonate (III). The condensation of 

(III) with 5-ethoxyindolin-2-one (IV) by means of tBu-OK in THF affords the spiro compound (V), which is 

deprotected with HCl in methanol to afford the spiranic alcohol (VI). The oxidation of (VI) with pyridinium 

chlorochromate (PCC) over Al2O3 provides the spiranic cyclohexanone (VII), which is treated with 2-

chloroethanol (VIII) and Ms-OH in toluene to give the ketal (IX). The reaction of (IX) with zinc borohydride 

and trimethylsilyl chloride in ethyl ether/dichloromethane yields the 2-chloroethoxy derivative (X), which is 

condensed with 4-(N-tert-butylcarbamoyl)-2-methoxybenzenesulfonyl chloride (XI) by means of tBu-OK in THF to 

afford the adduct (XII). Finally, the target compound is obtained by condensation of (XII) with morpholine 

(XIII) by means of NaI in DMF, followed by treatment with fumaric acid.

尼朦尔可素  包装:50克/瓶 价格:1300元/瓶 红色粉末

还阳碱 CAS号：  8600元/公斤

金阳碱 CAS号：54060-92-3   4600元/公斤

新阳碱    36-12-87  4600元/公斤

虾青素 CAS号：472-61-7   8600元/公斤 

CAS号：

MAB-CHMINAC

5FADB      

FUB-AMB   

CAS号：70434-92-3 CP 47,497 CAS号：952016-47-6 8492312-32-2

CAS号：84485-00-7 12 125494-59-9 CAS： CAS：

原料与成品三包服务: CAS:90717-16-1;299-42-3;6740-85-81867-66-9;51062-14-7; CAS:2114-00-3;2011-67-8;5650-44-

2;103-79-7 CAS:4468-48-8;103-79-7;51-57-0;6740-88-1;936-59-4;60124-79-0;125-79-1 CAS:76-99-3;118-92-3;2538-

50-3;340-56-7;82-58-6;51753-57-2;58-08-2